Clinical outcomes and recurrence patterns in pancreatic ductal adenocarcinoma diagnosed at an early stage: insights from a multicenter cohort study in Japan

Patients with early-stage PDAC exhibit a higher risk of remnant pancreatic recurrence than those with stage II disease. These findings underscore the importance of long-term pancreas-focused surveillance in early-stage PDAC to enable timely detection of late recurrence and potentially improve patients outcomes.

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Publication Details

Journal
Journal of Gastroenterology
Published
2026-01-03
DOI
https://doi.org/10.1007/s00535-025-02340-x
Primary Topic
Pancreatic and Hepatic Oncology Research
Type
article
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article

Clinical outcomes and recurrence patterns in pancreatic ductal adenocarcinoma diagnosed at an early stage: insights from a multicenter cohort study in Japan

Koji Arihiro, Tamito Sasaki, Shinya Nakamura, Akihito OKAZAKI et al.
Journal of Gastroenterology
Pancreatic and Hepatic Oncology Research
article

Clinical outcomes and recurrence patterns in pancreatic ductal adenocarcinoma diagnosed at an early stage: insights from a multicenter cohort study in Japan

Koji Arihiro, Tamito Sasaki, Shinya Nakamura, Akihito OKAZAKI, Kenichiro Uemura, Teruo Mouri, Bunjiro Noma, Juri Ikemoto, Yoshifumi Fujimoto, Yasutaka Ishii, Tomoyuki Minami, Shinya Takahashi, Shiro Oka, Keiji Hanada, Atsushi Yamaguchi, Masanobu Yukutake
article en

Abstract

Patients with early-stage PDAC exhibit a higher risk of remnant pancreatic recurrence than those with stage II disease. These findings underscore the importance of long-term pancreas-focused surveillance in early-stage PDAC to enable timely detection of late recurrence and potentially improve patients outcomes.

Journal of GastroenterologyVol. 61(3)
Hiroshima University (JP), Hiroshima General Hospital (JP), Hiroshima City Asa Citizens Hospital (JP), Hiroshima Red Cross Hospital & Atomic-bomb Survivors Hospital (JP), Hiroshima Prefectural Hospital (JP), Hiroshima University Hospital (JP), Kure Kyosai Hospital (JP), Higashihiroshima Medical Center (JP), Chugoku Rosai Hospital (JP), Kure Medical Center (JP), Onomichi General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 99%
Pancreatic and Hepatic Oncology Research
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Clinical outcomes and recurrence patterns in pancreatic ductal adenocarcinoma diagnosed at an early stage: insights from a multicenter cohort study in Japan — Koji Arihiro, Tamito Sasaki, et al. · Journal of Gastroenterology (2026) | TGRS Research Map | TGRS