Bladder Paraganglioma With Rapid Metastasis: A Case Report and Review of the Literature

Bladder paragangliomas (bPGLs) are extremely rare tumors, and we present a unique case of metastatic bPGL that developed within three months. Frequently, these tumors are related to a hereditary syndrome due to germline mutations in succinate dehydrogenase B (SDHB). A unique challenge in this case was related to social determinants of health, which, in this patient, were associated with difficulty maintaining appointments. In treating a patient with hematuria, it is important to consider paraganglioma (PGL) as a differential diagnosis to optimize treatment.

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Publication Details

Journal
Cureus
Published
2026-01-03
DOI
https://doi.org/10.7759/cureus.100705
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.00
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article

Bladder Paraganglioma With Rapid Metastasis: A Case Report and Review of the Literature

James Turney, Gabrielle R Yankelevich, Matvey Tsivian
Cureus
Adrenal and Paraganglionic Tumors
article

Bladder Paraganglioma With Rapid Metastasis: A Case Report and Review of the Literature

James Turney, Gabrielle R Yankelevich, Matvey Tsivian
article en

Abstract

Bladder paragangliomas (bPGLs) are extremely rare tumors, and we present a unique case of metastatic bPGL that developed within three months. Frequently, these tumors are related to a hereditary syndrome due to germline mutations in succinate dehydrogenase B (SDHB). A unique challenge in this case was related to social determinants of health, which, in this patient, were associated with difficulty maintaining appointments. In treating a patient with hematuria, it is important to consider paraganglioma (PGL) as a differential diagnosis to optimize treatment.

CureusVol. 18(1)
Rocky Vista University (US), Medical University of South Carolina (US)
Good health and well-being
Openalex Percentile: Top 98%
Adrenal and Paraganglionic Tumors
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