Natural triterpenic phenolic esters target PfA-M17 in Plasmodium falciparum
Further structure-activity and medicinal chemistry studies are warranted to elaborate on these findings and the potential for 8TTE-related molecules to serve as future antimalarial drugs.
Authors
- Joanne Bero (ORCID: https://orcid.org/0000-0002-6020-1424)
- M Frédérich
- Claire Beaufay (ORCID: https://orcid.org/0000-0002-0942-4649)
- Marjorie Schmitt
- Lúcia Mamede (ORCID: https://orcid.org/0000-0001-8206-8102)
- Manuel Llinás (ORCID: https://orcid.org/0000-0002-6173-5882)
- Gabriel W. Rangel (ORCID: https://orcid.org/0000-0002-8208-2817)
- Sébastien Albrecht (ORCID: https://orcid.org/0000-0002-1016-0193)
- Martin Spichty (ORCID: https://orcid.org/0000-0002-2533-9073)
- Isabelle Florent (ORCID: https://orcid.org/0000-0002-7140-6417)
- Joëlle Quetin-Leclercq
Institutions
- Centre National de la Recherche Scientifique (FR)
- Pennsylvania State University (US)
- University of Liège (BE)
- Université de Haute-Alsace (FR)
- Molécules de Communication et Adaptation des Micro-organismes (FR)
- UCLouvain (BE)
Publication Details
- Journal
- Malaria Journal
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1186/s12936-025-05762-3
- Primary Topic
- Marine Sponges and Natural Products
- Type
- article
- Field-Weighted Citation Impact
- 0.00