Prominent urinary dysfunction and delayed antibody detection in patients with glial fibrillary acidic protein astrocytopathy: a case series analysis

This case series underscores the high frequency of autonomic urinary dysfunction and the potential for delayed antibody detection in Chinese GFAP-A patients. These findings suggest that clinical suspicion should remain high even with initial negative antibody testing, warranting repeat CSF analysis in suspected cases to avoid diagnostic delay.

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Publication Details

Journal
BMC Neurology
Published
2026-01-02
DOI
https://doi.org/10.1186/s12883-025-04606-6
Primary Topic
Autoimmune Neurological Disorders and Treatments
Type
article
Field-Weighted Citation Impact
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article

Prominent urinary dysfunction and delayed antibody detection in patients with glial fibrillary acidic protein astrocytopathy: a case series analysis

Fei Gao, Yiming Zheng, Hongjun Hao, Zhenyu Niu et al.
BMC Neurology
Autoimmune Neurological Disorders and Treatments
article

Prominent urinary dysfunction and delayed antibody detection in patients with glial fibrillary acidic protein astrocytopathy: a case series analysis

Fei Gao, Yiming Zheng, Hongjun Hao, Zhenyu Niu, Nan Zhang, Li Fan, Lina Wei, Yunchuang Sun, Haiqiang Jin, Jing Guo, Ran Liu
article en

Abstract

This case series underscores the high frequency of autonomic urinary dysfunction and the potential for delayed antibody detection in Chinese GFAP-A patients. These findings suggest that clinical suspicion should remain high even with initial negative antibody testing, warranting repeat CSF analysis in suspected cases to avoid diagnostic delay.

BMC NeurologyVol. 26(1)
Peking University (CN), Peking University First Hospital (CN)
Openalex Percentile: Top 99%
Autoimmune Neurological Disorders and Treatments
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