Performance of clinical prediction models for identifying postmenopausal osteoporosis: a systematic review and meta-analysis

We found that the PMOP prediction models demonstrated promising performance. However, this review also highlights several potential limitations of current approaches, including a high risk of bias and limited external validation. Future research should aim to refine these models using larger and more diverse populations, as well as by incorporating additional risk factors to improve their clinical applicability.

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Publication Details

Journal
BMC Musculoskeletal Disorders
Published
2026-01-03
DOI
https://doi.org/10.1186/s12891-025-09389-y
Primary Topic
Bone health and osteoporosis research
Type
article
Field-Weighted Citation Impact
0.00
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article

Performance of clinical prediction models for identifying postmenopausal osteoporosis: a systematic review and meta-analysis

Wei Xü, Yanming Xie, Y Z Zhang, Xiangyun Guo et al.
BMC Musculoskeletal Disorders
Bone health and osteoporosis research
article

Performance of clinical prediction models for identifying postmenopausal osteoporosis: a systematic review and meta-analysis

Wei Xü, Yanming Xie, Y Z Zhang, Xiangyun Guo, Chuanrui Sun, Yuhui Yin, Yiwen Gan, Liang Wang, Jinran Qin, Xinyi Huang, Ming Chen, Yunning Li, Yang Guo
article en

Abstract

We found that the PMOP prediction models demonstrated promising performance. However, this review also highlights several potential limitations of current approaches, including a high risk of bias and limited external validation. Future research should aim to refine these models using larger and more diverse populations, as well as by incorporating additional risk factors to improve their clinical applicability.

BMC Musculoskeletal DisordersVol. 27(1)
Nanjing University of Chinese Medicine (CN), Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Wangjing Hospital of China Academy of Chinese Medical Sciences (CN), Nanjing Medical University (CN)
Openalex Percentile: Top 99%
Bone health and osteoporosis research
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