Iceberg phenomenon in cutaneous leishmaniasis: A sporotrichoid clue
We present a 29-year-old immunocompetent Uzbek woman with an ulcerated nodular lesion on her arm following an insect bite, caused by Leishmania major and confirmed by polymerase chain reaction (RT-PCR). The patient was initially treated with oral itraconazole and topical imiquimod. However, the disease progressed over 3 months and systemic liposomal amphotericin B was subsequently initiated. Magnetic resonance imaging (MRI) revealed deep tissue involvement, marking the first such finding in sporotrichoid cutaneous leishmaniasis caused by L major. This case emphasises the diagnostic and treatment challenges of atypical cutaneous leishmaniasis and highlights the value of imaging techniques in assessing disease extent.
Authors
- Mustafa Ozates
- Gokhan Okan
Institutions
- Istanbul Aydın University (TR)
- Advanced Imaging Research (United States) (US)
Publication Details
- Journal
- Clinical Medicine
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1016/j.clinme.2025.100551
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00