Intracranial Candida Auris Infection: A Case Report and Scoping Review
Key themes include 1) neurosurgical devices markedly increase CNS C. auris risk, 2) rapid diagnostics and susceptibility-guided therapy are imperative, 3) regimens targeting both systemic and CNS compartments may improve outcomes, and 4) device management is critical. Standardized protocols, multicenter registries, and pharmacokinetic studies are needed to guide treatment of this emerging, life-threatening infection.
Authors
- Laura B. Ngwenya (ORCID: https://orcid.org/0000-0001-7103-971X)
- Gabriel Jelkin
- Allie L. Heineman
- Henry T. Beckett
- Christopher M. Goddard CNP
Institutions
- Neurological Surgery (US)
- University of Cincinnati Medical Center (US)
Publication Details
- Journal
- World Neurosurgery
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1016/j.wneu.2025.124775
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00