Collagen Proportionate Area and Histological Grading of Fibrosis as Predictors of Clinical Outcomes and Mortality in Patients with Steatotic Liver Disease
CPA closely correlates with fibrosis stage and has comparable long-term prognostic value in SLD. Interpretation of study results is limited by the small sample size and low number of liver-specific events. Larger studies are needed to validate CPA's clinical utility and explore its integration into routine practice.
Authors
- Laust Hvas Mortensen (ORCID: https://orcid.org/0000-0002-6399-495X)
- Pernille Yde (ORCID: https://orcid.org/0000-0003-4412-8084)
- Andreas Bartholdy
- Birgitte Martine Viuff (ORCID: https://orcid.org/0000-0002-1676-2531)
- Majken K. Jensen (ORCID: https://orcid.org/0000-0003-4729-7545)
- Lise Lotte Gluud
- Elisabeth Douglas Galsgaaard
Institutions
- University of Copenhagen (DK)
- Novo Nordisk (Denmark) (DK)
- Hvidovre Hospital (DK)
- Copenhagen University Hospital (DK)
- Technical University of Denmark (DK)
Publication Details
- Journal
- Journal of Clinical and Experimental Hepatology
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1016/j.jceh.2025.103464
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer
- AstraZeneca
- Alexion Pharmaceuticals
- Novo Nordisk
- Novo Nordisk Fonden
- Swedish Orphan Biovitrum