Understanding how bacterial cell wall peptidoglycan metabolism can be used to develop antimicrobial strategies
The future of the field should benefit immensely from computational and AI-driven methodologies, combinatorial therapies reducing the risk of development of resistance and acknowledging that we have been screening poorly adapted chemical spaces for antibiotic discovery.
Authors
- Ivo G. Boneca (ORCID: https://orcid.org/0000-0001-8122-509X)
- Thomas Delerue (ORCID: https://orcid.org/0000-0002-8900-247X)
- Emma Melotti
Institutions
- Laboratoire de Chimie Bactérienne (FR)
Publication Details
- Journal
- Expert Opinion on Therapeutic Targets
- Published
- 2025-12-02
- DOI
- https://doi.org/10.1080/14728222.2025.2608020
- Primary Topic
- Bacterial Genetics and Biotechnology
- Type
- article
- Field-Weighted Citation Impact
- 0.00