From trial to real life: ten-year impact of a nutraceutical strategy on duodenal polyp burden in familial adenomatous polyposis
Continuous Adipol supplementation is associated with sustained reduction in duodenal polyp burden in FAP patients. Although the non-randomised, single-center design limits generalizability, these findings support nutritional chemoprevention as a valuable adjunct strategy in FAP. Multicenter randomised trials and biomarker studies are warranted.
Authors
- Laura Melotti (ORCID: https://orcid.org/0009-0003-9736-9030)
- Sabino Russi (ORCID: https://orcid.org/0000-0002-4467-4942)
- Carlo Calabrese (ORCID: https://orcid.org/0000-0003-3657-4463)
- Simona Laurino (ORCID: https://orcid.org/0000-0002-5220-3227)
- Fabiana Crispo (ORCID: https://orcid.org/0000-0001-5712-5021)
- Fernando Rizzello
- Nikolas Kostantine Dussias
Institutions
- Centro di Riferimento Oncologico della Basilicata (IT)
- Azienda USL di Bologna (IT)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-02
- DOI
- https://doi.org/10.3389/fonc.2025.1676394
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Ministero della Salute