Hormonal Contraceptive Use, Stress Disorders, and Cardiovascular and Thrombotic Risk in Women
In this retrospective cohort study, combined hormonal contraceptive use was associated with lower cardiovascular risk in women regardless of depression or anxiety. These protective associations did not extend to women with PTSD, suggesting that there are unique cardiovascular processes in the context of this stress-related disorder and hormonal contraceptive use that warrant further research.
Authors
- Jordan L. Thomas (ORCID: https://orcid.org/0000-0002-3881-6158)
- Michael T. Osborne (ORCID: https://orcid.org/0000-0003-1001-1718)
- Antonia V. Seligowski (ORCID: https://orcid.org/0000-0001-6946-6376)
- Shady Abohashem (ORCID: https://orcid.org/0000-0002-5033-8881)
- Maureen J. MacDonald (ORCID: https://orcid.org/0000-0001-9851-3610)
- Robyn A. Ellis (ORCID: https://orcid.org/0000-0003-0623-7378)
- K. K. Miller
- Rachel Rosovsky (ORCID: https://orcid.org/0000-0002-2392-7365)
- Ahmed Tawakol
- Anahita Dua (ORCID: https://orcid.org/0000-0002-3349-4233)
- Emily S. Lau
- Krystel AbiKaram
- Suzanne L. Pineles
Institutions
- Boston University (US)
- Harvard University (US)
- University of Kansas (US)
- McLean Hospital (US)
- VA Boston Healthcare System (US)
- Massachusetts General Hospital (US)
- National Center for PTSD (US)
- McMaster University (CA)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.51878
- Primary Topic
- Sex and Gender in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00