15-Day Duration of Venetoclax Combined with Azacitidine in Treatment-Naive Higher-Risk Myelodysplastic Syndromes: A Prospective Multicenter Study

The 15-day venetoclax plus azacitidine regimen demonstrated high efficacy and manageable toxicity in treatment-naïve HR-MDS. It may be particularly beneficial for patients with high neutrophil counts, adverse cytogenetics, or those eligible for HSCT, supporting further investigation in larger trials.

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Publication Details

Journal
Cancers
Published
2026-01-02
DOI
https://doi.org/10.3390/cancers18010159
Primary Topic
Acute Myeloid Leukemia Research
Type
article
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article

15-Day Duration of Venetoclax Combined with Azacitidine in Treatment-Naive Higher-Risk Myelodysplastic Syndromes: A Prospective Multicenter Study

Yongcheng Sun, Ping Zhang, Yu Wang, Liping Mao et al.
Cancers
Acute Myeloid Leukemia Research
article

15-Day Duration of Venetoclax Combined with Azacitidine in Treatment-Naive Higher-Risk Myelodysplastic Syndromes: A Prospective Multicenter Study

Yongcheng Sun, Ping Zhang, Yu Wang, Liping Mao, Baodong YaoYujie YanXianwu Ye, Guifang Ouyang, Yinjun LOU, BinBin Lai, Lixia Sheng, Chen Mei, Hongyan Tong, Jin Zhang, De Zhou, Lieguang Chen, Huafeng Wang, Wenyuan Mai, Xiao Yan, Wanzhuo Xie, Huifang Jiang, Shanhao Tang, Liya Ma, Wenjun Wu
article en

Abstract

The 15-day venetoclax plus azacitidine regimen demonstrated high efficacy and manageable toxicity in treatment-naïve HR-MDS. It may be particularly beneficial for patients with high neutrophil counts, adverse cytogenetics, or those eligible for HSCT, supporting further investigation in larger trials.

CancersVol. 18(1)
Sir Run Run Shaw Hospital (CN), Zhejiang Provincial Hospital of TCM (CN), Tongde Hospital of Zhejiang Province (CN), Hangzhou Hospital of Traditional Chinese Medicine (CN), Ningbo University Affiliated Hospital (CN), Ningbo First Hospital (CN), First Affiliated Hospital Zhejiang University (CN)
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Openalex Percentile: Top 99%
Acute Myeloid Leukemia Research
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15-Day Duration of Venetoclax Combined with Azacitidine in Treatment-Naive Higher-Risk Myelodysplastic Syndromes: A Prospective Multicenter Study — Yongcheng Sun, Ping Zhang, et al. · Cancers (2026) | TGRS Research Map | TGRS