Multicenter, double-blind, sham endoscopy-controlled, randomized trial evaluating the efficacy of antireflux mucosal ablation for the treatment of gastroesophageal reflux disease

ARMA was not superior to sham endoscopy in improving GERD-related quality of life at 12 months in patients with PPI-responsive GERD, and was associated with a higher incidence of adverse events. These findings do not support its implementation in routine clinical practice.

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Publication Details

Journal
Endoscopy
Published
2025-12-31
DOI
https://doi.org/10.1055/a-2780-0706
Primary Topic
Gastroesophageal reflux and treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Multicenter, double-blind, sham endoscopy-controlled, randomized trial evaluating the efficacy of antireflux mucosal ablation for the treatment of gastroesophageal reflux disease

Faust Riu, F. Estremera-Arévalo, Peña Redondo, Julia Arribas Anta et al.
Endoscopy
Gastroesophageal reflux and treatments
article

Multicenter, double-blind, sham endoscopy-controlled, randomized trial evaluating the efficacy of antireflux mucosal ablation for the treatment of gastroesophageal reflux disease

Faust Riu, F. Estremera-Arévalo, Peña Redondo, Julia Arribas Anta, H. Nuñez Rodriguez, A. Albillos, José María Duque Alcorta, EDUARDO ALBENIZ, Isabel Castel de Lucas, I. Pérez Enciso, JC Marín-Gabriel, Juan E. Naves, Íngrid Marín, Daniel Pérez Corte, Pedro de María, Alberto Herreros de Tejada, Vicente Lorenzo-Zúñiga, Hugo Uchima, Covadonga García-Suárez, Alfonso Muriel, Oscar Nogales, Carlos Teruel Sanchez-Vegazo, Amaia Arrubla Gamboa, Ismael El Haira Martínez, Enrique Rodriguez de Santiago, ECA-ARMA authors of the Mucosal Resection and Third-Space Endoscopy SEED Working Group
article en

Abstract

ARMA was not superior to sham endoscopy in improving GERD-related quality of life at 12 months in patients with PPI-responsive GERD, and was associated with a higher incidence of adverse events. These findings do not support its implementation in routine clinical practice.

Endoscopy
Universidad de Alcalá (ES), Hospital Universitario La Paz (ES), Hospital General Universitario Gregorio Marañón (ES), Hospital Universitari i Politècnic La Fe (ES), Research Institute Hospital 12 de Octubre (ES), Hospital Universitario San Agustín (ES), Hospital Universitario 12 De Octubre (ES), Hospital Universitario Puerta de Hierro Majadahonda (ES), Navarrabiomed (ES), Instituto Ramón y Cajal de Investigación Sanitaria (ES), Hospital Del Mar (ES), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES), Hospital Universitario De Cabueñes (ES), Hospital Universitari Germans Trias i Pujol (ES), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Hospital Universitario Río Hortega (ES), Hospital Universitario Ramón y Cajal (ES), Instituto de Investigación Sanitaria La Fe (ES), Universidad Autónoma de Madrid (ES)
Openalex Percentile: Top 25%
Gastroesophageal reflux and treatments
DOISourceOpenAlex
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