Miller Fisher Variant of Guillain-Barré Syndrome Presenting With Dysphagia and Ophthalmoplegia
Miller Fisher syndrome (MFS) is a rare variant of Guillain-Barré syndrome (GBS). It is characterized by a triad of ataxia, areflexia, and ophthalmoparesis. Akin to GBS, it is often triggered by a respiratory infection, causing immune cross-activation against pathogenic proteins and gangliosides. Symptoms typically occur in chronological progression, beginning with ophthalmoparesis, then ataxia, and finally areflexia. Our case is of a patient presenting with dysphagia and ophthalmoplegia as the initial manifestations. There currently exist only a limited number of reported cases of MFS presenting with dysphagia, which, along with ophthalmoplegia, areflexia, and ataxia, should raise suspicion for MFS.
Authors
- Rupam Sharma (ORCID: https://orcid.org/0000-0003-3457-4371)
- Sanjana Murdande
- Jose Garcia-Corella
- Arin Orogian
- Linh Tran
Institutions
- Kern Medical Center (US)
Publication Details
- Journal
- Cureus
- Published
- 2026-01-02
- DOI
- https://doi.org/10.7759/cureus.100614
- Primary Topic
- Peripheral Neuropathies and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00