Transition of oral microbiome profile in HIV-infected Indonesian patients: the role of antiretroviral therapy
HIV infection is associated with a distinct oral dysbiosis characterised by an increase in opportunistic pathogens and reduction in commensal bacteria. HIV-on-ART individuals show a transitional shift towards the HIV-negative oral microbiome profiles. Our findings suggest that biological and/or demographic factors coupled to oral microbiome profiles may facilitate targeted interventions in the personalised management of oral health for individuals living with HIV.
Authors
- Natalia Rasta Malem
- John P. Hays (ORCID: https://orcid.org/0000-0001-9183-4497)
- Nathanael Ibot David (ORCID: https://orcid.org/0000-0003-1021-2755)
- Nikolaos Strepis (ORCID: https://orcid.org/0000-0002-0997-8430)
- Agustin Iskandar (ORCID: https://orcid.org/0000-0001-9204-1958)
- Jan Nouwen (ORCID: https://orcid.org/0000-0002-0106-4490)
- Lita Setyowatie (ORCID: https://orcid.org/0000-0002-5274-7873)
- Milanitalia Gadys Rosandy
- H. Bing Thio
- Handono Kalim
- Tamar E. Nijsten
- Aulia Rahmi Prawesti
- Indah Adhita Wulanda
- Muhammad Anshory
Institutions
- University of Brawijaya (ID)
- Erasmus MC (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- Journal of Oral Microbiology
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1080/20002297.2025.2609445
- Primary Topic
- HIV/AIDS oral health manifestations
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Brawijaya
- Lembaga Pengelola Dana Pendidikan