Discrepancies in the Detection of PML::RARA Gene Rearrangement by Fluorescent In Situ Hybridization Using Commonly Used Dual Color Dual Fusion Probes
These findings reveal limitations in commonly used <i>PML::RARA</i> FISH probes and support reflex testing with alternative probes and molecular confirmation to ensure accurate diagnosis.
Authors
- Shivani Golem
- Karsten Evans
- Sydney Graham
- Hanan S. Elsarraj (ORCID: https://orcid.org/0000-0001-9926-7167)
Institutions
- Loyola University Medical Center (US)
- University of Kansas Medical Center (US)
- Kansas City VA Medical Center (US)
Publication Details
- Journal
- Diseases
- Published
- 2026-01-02
- DOI
- https://doi.org/10.3390/diseases14010017
- Primary Topic
- Retinoids in leukemia and cellular processes
- Type
- article
- Field-Weighted Citation Impact
- 0.00