Longitudinal three-photon imaging for tracking amyloid plaques and vascular degeneration in a mouse model of Alzheimer’s disease
We demonstrate the potential of three-photon imaging to track vascular and amyloid-related changes in deep cortical structures. It offers a tool for studying the interplay between vascular and amyloid pathologies in AD, supporting future research into disease mechanisms and therapeutic strategies.
Authors
- Simon R. Schultz (ORCID: https://orcid.org/0000-0002-6794-5813)
- Mengke Yang
- Mary Ann Go
- Eline Stas
Institutions
- London Centre for Nanotechnology (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1117/1.jbo.31.1.016004
- Primary Topic
- Alzheimer's disease research and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00