Multienergy x-ray imaging enabled by unipolar perovskite detector for intelligent substance identification

A challenge with state-of-the-art projection x-ray imaging technologies is their limited ability to identify unknown substances. Here, we develop an intelligent multienergy x-ray imaging technique capable of precisely distinguishing different substances and labeling them with diverse colors. Our design uses a series of x-ray attenuation coefficient ratios under different x-ray energies as substance-specific markers. For this purpose, unipolar perovskite x-ray detectors are carefully engineered to resolve the x-ray energies into seven channels using a customized algorithm. Combining machine learning and a comprehensive x-ray attenuation ratio database of common materials enables accurate recognition of low-density biological tissues composed of light elements with similar atomic numbers. By transforming the intensity scale in conventional x-ray images into an attenuation coefficient ratio, our work presents a proof of concept for color-coded x-ray imaging, highlighting its potential for applications in energy-dispersive computed tomography, targeted drug delivery, quantum physics, and universe exploration.

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Publication Details

Journal
Science Advances
Published
2026-01-02
DOI
https://doi.org/10.1126/sciadv.adz0228
Citations
1
Primary Topic
Advanced X-ray and CT Imaging
Type
article
Field-Weighted Citation Impact
21.28
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article

Multienergy x-ray imaging enabled by unipolar perovskite detector for intelligent substance identification

Shilin Liu, Lu Xue, Su Yan, YuWei Li et al.
1 citations
Science Advances
Advanced X-ray and CT Imaging
21.28
article

Multienergy x-ray imaging enabled by unipolar perovskite detector for intelligent substance identification

Shilin Liu, Lu Xue, Su Yan, YuWei Li, Ziyu Wei, S.D. Wang, Chengjun Liu, Sajid Hussain, Jun Zhao, Bingjian Zhu, Xiangyu Ou, Xiaobao Xu, Feng Gao, Wei Lei
article en
1 citations

Abstract

A challenge with state-of-the-art projection x-ray imaging technologies is their limited ability to identify unknown substances. Here, we develop an intelligent multienergy x-ray imaging technique capable of precisely distinguishing different substances and labeling them with diverse colors. Our design uses a series of x-ray attenuation coefficient ratios under different x-ray energies as substance-specific markers. For this purpose, unipolar perovskite x-ray detectors are carefully engineered to resolve the x-ray energies into seven channels using a customized algorithm. Combining machine learning and a comprehensive x-ray attenuation ratio database of common materials enables accurate recognition of low-density biological tissues composed of light elements with similar atomic numbers. By transforming the intensity scale in conventional x-ray images into an attenuation coefficient ratio, our work presents a proof of concept for color-coded x-ray imaging, highlighting its potential for applications in energy-dispersive computed tomography, targeted drug delivery, quantum physics, and universe exploration.

Science AdvancesVol. 12(1)
Linköping University (SE), Southeast University (CN), Nanjing University of Aeronautics and Astronautics (CN)
Good health and well-being
Openalex Percentile: Top 4%
Advanced X-ray and CT Imaging
21.28
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Multienergy x-ray imaging enabled by unipolar perovskite detector for intelligent substance identification — Shilin Liu, Lu Xue, et al. · Science Advances (2026) | TGRS Research Map | TGRS