Iron-Catalyzed Amination of Silyl Enol Ethers Using Hydroxylamine Derivatives
An iron-catalyzed intermolecular amination reaction is reported. This transformation proceeds under mild conditions through the combination of silyl enol ethers and hydroxylamine derivatives with a simple iron complex, enabling access to a broad range of α-amino carbonyl products.
Authors
- Guillaume Prestat (ORCID: https://orcid.org/0000-0002-3948-1476)
- Georgina Kirby (ORCID: https://orcid.org/0000-0002-5971-4038)
- Farouk Berhal (ORCID: https://orcid.org/0000-0003-4974-7810)
- G. R. Lee
- Fabienne Peyrot
- Laurence Grimaud
- Maxime R. Vitale
- Sonia Lajnef
Institutions
- École Nationale Supérieure de Chimie de Montpellier (FR)
- Centre National de la Recherche Scientifique (FR)
- Université Paris Cité (FR)
- Université Paris Sciences et Lettres (FR)
- Sorbonne Université (FR)
- Académie de Paris (FR)
- Laboratoire de Chimie et Biochimie Pharmacologiques et Toxicologiques (FR)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1021/acs.joc.5c02591
- Citations
- 1
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 22.95