Asymptomatic Aortic Regurgitation: Evolving Imaging Markers and Contemporary Intervention Strategies

Asymptomatic aortic regurgitation (AR) has traditionally been managed conservatively until symptom onset or overt left ventricular systolic dysfunction. However, adverse myocardial remodeling-detected by myocardial strain, volumetric cardiac magnetic resonance, and fibrosis imaging-often precedes current guideline thresholds for interventions and may be irreversible. Advances in multimodal imaging now enable earlier risk stratification beyond conventional metrics. In parallel, intervention strategies are evolving, including valve repair, valve-sparing root replacement, Ross procedure, and transcatheter aortic valve replacement in selected high-risk patients. This narrative review summarizes contemporary advances in imaging and intervention for asymptomatic AR, while critically appraising current evidentiary and technical limitations that constrain earlier intervention. The review is based on a narrative synthesis of the contemporary literature, drawing from recent clinical studies, imaging advances, and guideline documents rather than a systematic evidence search.

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Publication Details

Journal
Journal of Clinical Medicine
Published
2026-01-02
DOI
https://doi.org/10.3390/jcm15010339
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Asymptomatic Aortic Regurgitation: Evolving Imaging Markers and Contemporary Intervention Strategies

Chieh-Mei Tsai, Yu‐Jang Su, Shivam Singh, Chueh‐Hung Wu et al.
Journal of Clinical Medicine
Cardiac Valve Diseases and Treatments
article

Asymptomatic Aortic Regurgitation: Evolving Imaging Markers and Contemporary Intervention Strategies

Chieh-Mei Tsai, Yu‐Jang Su, Shivam Singh, Chueh‐Hung Wu, Kuan-Yu Lai, Li-Tan Yang, Casper H. H. Tsai
article en

Abstract

Asymptomatic aortic regurgitation (AR) has traditionally been managed conservatively until symptom onset or overt left ventricular systolic dysfunction. However, adverse myocardial remodeling-detected by myocardial strain, volumetric cardiac magnetic resonance, and fibrosis imaging-often precedes current guideline thresholds for interventions and may be irreversible. Advances in multimodal imaging now enable earlier risk stratification beyond conventional metrics. In parallel, intervention strategies are evolving, including valve repair, valve-sparing root replacement, Ross procedure, and transcatheter aortic valve replacement in selected high-risk patients. This narrative review summarizes contemporary advances in imaging and intervention for asymptomatic AR, while critically appraising current evidentiary and technical limitations that constrain earlier intervention. The review is based on a narrative synthesis of the contemporary literature, drawing from recent clinical studies, imaging advances, and guideline documents rather than a systematic evidence search.

Journal of Clinical MedicineVol. 15(1)
National Taiwan University (TW), Reading Hospital (US), Mayo Clinic in Arizona (US), National Taiwan University Hospital (TW)
National Taiwan University Hospital, National Taiwan University, National Science and Technology Council
Good health and well-being
Openalex Percentile: Top 99%
Cardiac Valve Diseases and Treatments
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Asymptomatic Aortic Regurgitation: Evolving Imaging Markers and Contemporary Intervention Strategies — Chieh-Mei Tsai, Yu‐Jang Su, et al. · Journal of Clinical Medicine (2026) | TGRS Research Map | TGRS