Interaction effect of rehabilitation initiation timing and hospitalization frequency on long-term functional outcomes after stroke in rural China: a retrospective cohort study
Earlier initiation and greater frequency of inpatient rehabilitation were independently associated with better ADL outcomes at the 6-month mark in rural Chinese stroke survivors. Importantly, the benefit of each additional rehabilitation admission was amplified when therapy began within the first month post-stroke and diminished when initiation was delayed beyond two months, especially among patients with hemorrhagic stroke, aged ≥65 years, women, and those with higher educational attainment.
Authors
- Luwen Zhang (ORCID: https://orcid.org/0009-0001-9273-2326)
- Juming Liu (ORCID: https://orcid.org/0000-0002-2252-0504)
- Qihan Sun (ORCID: https://orcid.org/0000-0003-2753-0768)
- Tao Qin (ORCID: https://orcid.org/0000-0001-7229-9353)
- Chao Zhang
- Changyu Ju
- Feng Wu
- Xiping Jia
Institutions
- Hubei University of Arts and Science (CN)
- Xiangyang Central Hospital (CN)
- Guangdong Polytechnic Normal University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2026-01-02
- DOI
- https://doi.org/10.3389/fneur.2025.1706724
- Primary Topic
- Stroke Rehabilitation and Recovery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guangdong Medical Research Foundation