Shared and Sex-Specific Genetic Risk for Parkinson’s Disease Risk Across European Populations
Overall, PD genetic architecture appears broadly similar between females and males, but the identification of five novel loci and significant differences at select regions highlights the value of sex-stratified analyses for uncovering additional genetic contributors to PD risk beyond those detected in combined analyses.
Authors
- The Global Parkinson's Genetics Program (GP2)
Institutions
- All Russian Research Institute of Hydrometeorological information World Data Center (RU)
Publication Details
- Journal
- medRxiv
- Published
- 2026-01-02
- DOI
- https://doi.org/10.64898/2025.12.29.25343160
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Health and Human Services
- Michael J. Fox Foundation for Parkinson's Research
- Amazon Web Services
- National Institutes of Health