Real-World Diagnostic and Therapeutic Insights in Transthyretin Cardiac Amyloidosis: Experience from the Black Sea Region of Türkiye

These findings align with emerging international real-world data from European, Japanese, and Hellenic cohorts, which consistently demonstrate that tafamidis treatment is associated with fewer clinical events and more stable functional status in patients with ATTR-CM. 7-10At the same time, our results highlight several context-specific challenges in Trkiye.First, the positive correlation between distance to the hospital and time to diagnosis suggests that patients in rural areas reach specialist care later, despite presenting with characteristic