Prehospital risk stratification in suspected non-ST-segment elevation acute coronary syndrome with point-of-care troponin: an individual patient data meta-analysis

In well-trained EMS systems, where prompt and accurate follow-up of low-risk patients is possible, HEART-derived CRS effectively identify patients with a very low risk of 30-day mortality and MACE. However, implementation in other healthcare systems requires additional validation, given the variations in healthcare structure, risk stratification processes and follow-up capabilities.

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Publication Details

Journal
Heart
Published
2026-01-02
DOI
https://doi.org/10.1136/heartjnl-2025-326922
Citations
1
Primary Topic
Acute Myocardial Infarction Research
Type
article
Field-Weighted Citation Impact
30.07
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article

Prehospital risk stratification in suspected non-ST-segment elevation acute coronary syndrome with point-of-care troponin: an individual patient data meta-analysis

Simon A. Mahler, Anna C. Snavely, Rudolf T Tolsma, Cetinyurek-Yavuz Aysun et al.
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Acute Myocardial Infarction Research
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article

Prehospital risk stratification in suspected non-ST-segment elevation acute coronary syndrome with point-of-care troponin: an individual patient data meta-analysis

Simon A. Mahler, Anna C. Snavely, Rudolf T Tolsma, Cetinyurek-Yavuz Aysun, Jesse P. A. Demandt, Marion Fokkert, Jamie G. Cooper, Pieter J. J. Vlaar, Veerle A E van Hattem, Dennis Sagel, Marcel van ’t Veer, N Van Royen, Cyril Camaro, Arnoud A. W. J. van ’t Hof, P Pim van der Harst, Lorna A A Donaldson
article en
1 citations

Abstract

In well-trained EMS systems, where prompt and accurate follow-up of low-risk patients is possible, HEART-derived CRS effectively identify patients with a very low risk of 30-day mortality and MACE. However, implementation in other healthcare systems requires additional validation, given the variations in healthcare structure, risk stratification processes and follow-up capabilities.

Heart
University Medical Center Groningen (NL), Radboud University Nijmegen (NL), University of Groningen (NL), University of Applied Sciences Utrecht (NL), Utrecht University (NL), University of Aberdeen (GB), Maastricht University Medical Centre (NL), Catharina Ziekenhuis (NL), Radboud University Medical Center (NL), University Medical Center Utrecht (NL), Maastricht University (NL), NHS Grampian (GB), Ambulance Care (Sweden) (SE), Netherlands Heart Institute (NL), Zuyderland Medisch Centrum (NL), Isala (NL), Wake Forest University (US), Eindhoven University of Technology (NL)
Good health and well-being
Openalex Percentile: Top 3%
Acute Myocardial Infarction Research
30.07
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