Production Of Antiseptic Using Firetail (Acalypha Amentacea) And Evaluation Of Its Antibacterial Activity

Abstract— This research focuses on the production of liquid antiseptic using Firetail (Acalypha amentacea) extract as a natural substitute for phenol, a common chemical disinfectant and evaluating its antibacterial activity. The study focuses on the formulation of a safer, eco-friendly antiseptic that retains strong antimicrobial properties. Firetail, known for its antibacterial and antifungal activity, was extracted using water and methanol and incorporated into a typical antiseptic formulation containing pine oil, isopropyl alcohol, texapon, and water. The product formed was evaluated for antimicrobial activity against Klebsiella pnuemoniae, and Staphylococcus aureus. Results showed that the Firetail-based antiseptic demonstrated significant antibacterial effects against the tested pathogens. Methanol based extract showed 4.7 mm and 4. 40 mm zones of inhibition against Klebsiella pnuemoniae, and Staphylococcus aureus. Water extract of the plant recorded 2.90 mm and 1.90 mm zones of inhibition against Klebsiella pnuemoniae and Staphylococcus aureus respectively. The formulation proved mild on skin and environmentally safe, suggesting that Firetail extract can effectively replace phenol in commercial antiseptic products. This work shows that locally sourced medicinal plants can be used in health-related formulations, reducing cost of purchasing chemicals and ensures environmental safety.