Perioperative laboratory profiles predict complications after extensive head and neck reconstruction: a proof-of-concept study
Given their multifactorial nature, influenced by comorbidities, tumor biology, and perioperative management, these findings highlight the need for longitudinal laboratory monitoring and prospective validation in controlled settings. Integrating dynamic laboratory trends into multimodal prediction models may facilitate earlier risk stratification and improve individualized perioperative management in head and neck reconstructive surgery.
Authors
- Julie Schanz (ORCID: https://orcid.org/0000-0003-2714-7072)
- Christoph Fischer (ORCID: https://orcid.org/0000-0002-7202-148X)
- Tatjana Khromov (ORCID: https://orcid.org/0000-0002-5340-9593)
- Ulrich Stefenelli
- Henning Schliephake
- Phillipp Brockmeyer
- Simon Breier
- Boris Schminke
Institutions
- Heidelberg University (DE)
- Nephrologisches Zentrum Goettingen (DE)
- University Medical Centre Mannheim (DE)
- Artificial Intelligence in Medicine (Canada) (CA)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-01-02
- DOI
- https://doi.org/10.3389/fonc.2025.1724846
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00