The use of large language models in generating multiple choice questions for health professions education: A systematic review and network meta-analysis

ChatGPT 4 may create similar quality MCQs to humans, whereas ChatGPT 3.5 and Llama 2 may be of worse quality. Further studies that directly compare these LLMs to human-generated questions and administer MCQs to students are required.

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Publication Details

Journal
PLoS ONE
Published
2026-01-02
DOI
https://doi.org/10.1371/journal.pone.0340277
Primary Topic
Artificial Intelligence in Healthcare and Education
Type
article
Field-Weighted Citation Impact
0.00
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article

The use of large language models in generating multiple choice questions for health professions education: A systematic review and network meta-analysis

Keean Nanji, Wesla Pfeifer, MOIZ LAKHANI, Lauren Riehm et al.
PLoS ONE
Artificial Intelligence in Healthcare and Education
article

The use of large language models in generating multiple choice questions for health professions education: A systematic review and network meta-analysis

Keean Nanji, Wesla Pfeifer, MOIZ LAKHANI, Lauren Riehm, Evelina Pankiv, Dean Hasanee
article en

Abstract

ChatGPT 4 may create similar quality MCQs to humans, whereas ChatGPT 3.5 and Llama 2 may be of worse quality. Further studies that directly compare these LLMs to human-generated questions and administer MCQs to students are required.

PLoS ONEVol. 21(1)
University of Ottawa (CA), University of Toronto (CA), Hospital for Sick Children (CA), Impact (CA), McMaster University (CA)
Openalex Percentile: Top 99%
Artificial Intelligence in Healthcare and Education
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