Suzetrigine, a selective NaV1.8 inhibitor in acute and chronic pain: mechanistic insights, clinical outcomes, and future perspectives
Suzetrigine represents a promising nonopioid alternative for acute pain and has the potential to fill a significant gap in pain management. While initial results are encouraging, future studies are needed to define its role in chronic pain and multimodal analgesia, and to establish long-term safety.
Authors
- Matthew W. Swisher (ORCID: https://orcid.org/0000-0003-2196-6288)
- Steven L. Chen
- Matthew A. Liu
Institutions
- University of San Diego (US)
- Veterans Health Administration (US)
- UC San Diego Health System (US)
Publication Details
- Journal
- Current Opinion in Anaesthesiology
- Published
- 2025-12-01
- DOI
- https://doi.org/10.1097/aco.0000000000001599
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00