SENP3/FIS1-regulated PFC neural mitochondrial fragmentation underlies the mechanism of electroacupuncture attenuating depressive behavior in CUMS mice

These evidences suggested that the antidepressant effects of EA may involve modulation of mitochondrial fragmentation regulated by the SENP3/FIS1 pathway in prefrontal cortex neurons.

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Publication Details

Journal
Frontiers in Psychiatry
Published
2026-01-02
DOI
https://doi.org/10.3389/fpsyt.2025.1645757
Primary Topic
Acupuncture Treatment Research Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

SENP3/FIS1-regulated PFC neural mitochondrial fragmentation underlies the mechanism of electroacupuncture attenuating depressive behavior in CUMS mice

Ningjing Lai, Feifei Li, Xiaoke Qiu, Zheng Zhang et al.
Frontiers in Psychiatry
Acupuncture Treatment Research Studies
article

SENP3/FIS1-regulated PFC neural mitochondrial fragmentation underlies the mechanism of electroacupuncture attenuating depressive behavior in CUMS mice

Ningjing Lai, Feifei Li, Xiaoke Qiu, Zheng Zhang, Jiandi Wu, Yü Huang, Ting Tu, Xin Li, Peilin Lin, Jiping Zhang, Shaoda Lai
article en

Abstract

These evidences suggested that the antidepressant effects of EA may involve modulation of mitochondrial fragmentation regulated by the SENP3/FIS1 pathway in prefrontal cortex neurons.

Frontiers in PsychiatryVol. 16
Guangzhou University of Chinese Medicine (CN), TCM-Intigrated Cancer Center of Southern Medical University (CN), Southern Medical University (CN)
Good health and well-being
Openalex Percentile: Top 98%
Acupuncture Treatment Research Studies
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