Self-resolution of spontaneous epidural hematoma in sickle cell anemia: A case report

Spontaneous epidural hematoma is a rare and dangerous complication of sickle cell anemia which typically requires surgical management. We present a rare case of a patient with sickle cell anemia and intracranial spontaneous epidural hematoma which resolved without any surgical intervention. We hypothesize the hemorrhage was due to skull bone infarction from sickle cell anemia. Clinicians and radiologists should be aware of rare non-surgical resolution of epidural hemorrhage in patients with sickle cell anemia.

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Publication Details

Journal
Radiology Case Reports
Published
2026-01-02
DOI
https://doi.org/10.1016/j.radcr.2025.11.079
Primary Topic
Hemoglobinopathies and Related Disorders
Type
article
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article

Self-resolution of spontaneous epidural hematoma in sickle cell anemia: A case report

Ameya Nayate, Shruti Kumari, Grayson H. Hooper
Radiology Case Reports
Hemoglobinopathies and Related Disorders
article

Self-resolution of spontaneous epidural hematoma in sickle cell anemia: A case report

Ameya Nayate, Shruti Kumari, Grayson H. Hooper
article en

Abstract

Spontaneous epidural hematoma is a rare and dangerous complication of sickle cell anemia which typically requires surgical management. We present a rare case of a patient with sickle cell anemia and intracranial spontaneous epidural hematoma which resolved without any surgical intervention. We hypothesize the hemorrhage was due to skull bone infarction from sickle cell anemia. Clinicians and radiologists should be aware of rare non-surgical resolution of epidural hemorrhage in patients with sickle cell anemia.

Radiology Case ReportsVol. 21(3)
University Hospitals of Cleveland (US), Case Western Reserve University (US)
Good health and well-being
Openalex Percentile: Top 99%
Hemoglobinopathies and Related Disorders
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