Analysis of common differential gene expression between rheumatoid arthritis and ulcerative colitis
The results of this study reveal potential common molecular mechanisms underlying rheumatoid arthritis (RA) and ulcerative colitis (UC). The key target genes CCR7, CD19, CXCL13, CXCR4, and SELL highlight common underlying factors associated with both diseases. Further investigation and exploration of these findings can pave the way for new candidate targets and directions in therapeutic research aimed at treating RA and UC. This study emphasizes the importance of utilizing bioinformatics approaches to uncover the mechanisms of complex diseases, providing a promising pathway for the development of more effective and targeted treatments.
Authors
- Chang-sheng Liao
- Weirong Cui
- Fang-zheng He
- Tao Wu
- Peng-fei Han
Institutions
- Changzhi Medical College (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1371/journal.pone.0339397
- Primary Topic
- Rheumatoid Arthritis Research and Therapies
- Type
- article
- Field-Weighted Citation Impact
- 0.00