The timing of concurrent intrathecal chemotherapy during blinatumomab infusion influences neurotoxicity in pediatric acute lymphoblastic leukemia

Initiating IT chemotherapy on the same day as blinatumomab infusion significantly increases the risk of neurotoxicity in pediatric ALL patients.

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Publication Details

Journal
Frontiers in Immunology
Published
2026-01-02
DOI
https://doi.org/10.3389/fimmu.2025.1690916
Primary Topic
Acute Lymphoblastic Leukemia research
Type
article
Field-Weighted Citation Impact
0.00
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article

The timing of concurrent intrathecal chemotherapy during blinatumomab infusion influences neurotoxicity in pediatric acute lymphoblastic leukemia

B. Liu, Guotao Guan, Qi Wang, Y P Dai et al.
Frontiers in Immunology
Acute Lymphoblastic Leukemia research
article

The timing of concurrent intrathecal chemotherapy during blinatumomab infusion influences neurotoxicity in pediatric acute lymphoblastic leukemia

B. Liu, Guotao Guan, Qi Wang, Y P Dai, Liying Liu
article en

Abstract

Initiating IT chemotherapy on the same day as blinatumomab infusion significantly increases the risk of neurotoxicity in pediatric ALL patients.

Frontiers in ImmunologyVol. 16
Shandong Provincial Hospital (CN), Shandong First Medical University (CN)
Good health and well-being
Openalex Percentile: Top 99%
Acute Lymphoblastic Leukemia research
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