Profile of Blood Biomarkers in Febrile Infants Under 90 Days Old With Invasive Bacterial Infection by Type of Infection and Causing Bacteria: A Multicenter Study
Biomarker levels in young febrile infants with IBIs depend on IBI type and causing bacteria. Increases in WBC, ANC and C-reactive protein are lower in isolated bacteremias than in bacteremic urinary tract infections. Procalcitonin is the best biomarker for ruling out S. agalactiae IBIs. These distinctions are key to interpreting lab tests and preventing underdiagnosis of invasive infections.
Authors
- Laia Sánchez-Torrent
- Ana M. Borrull-Senra
- Vanessa Bonil
- Ana Fustiñana (ORCID: https://orcid.org/0000-0002-1447-0455)
- Diana Paola Gallardo Martínez (ORCID: https://orcid.org/0009-0002-0987-089X)
- Adriana Yock‐Corrales (ORCID: https://orcid.org/0000-0002-8251-2434)
- Amaia Cámara (ORCID: https://orcid.org/0000-0001-9805-0097)
- Viviana Pavlicich
- Anna Sorolla-Anglés
- Cristina López (ORCID: https://orcid.org/0000-0001-7036-7308)
- Tomás Giménez-Galache
- Susanna Hernández-Bou
- Jose Antonio Alonso-Cadenas
- Lucía Garriga (ORCID: https://orcid.org/0000-0001-9761-1040)
- Marianela Lourdes Orpianesi
- Patricia Domínguez-Llamas
- Eugenia Hernandez
- Roberto Velasco
- Héctor Manuel Dávila-Ramirez
- María Soledad Tortora-Saldarini
- Rocío Rodrigo
- Julio Baena-Baca (ORCID: https://orcid.org/0009-0003-6208-5601)
- Maria Concepción Villalón
- Borja Gómez
Institutions
- Hebron University (PS)
- Hospital Sant Joan de Déu Barcelona (ES)
- University College Cork (IE)
- Garrahan Hospital (AR)
- Centro Hospitalario Pereira Rossell (UY)
- Hospital Universitario de Canarias (ES)
- Hospital Italiano de Buenos Aires (AR)
- BioCruces Health research Institute (ES)
- Complejo Hospitalario de Navarra (ES)
- Consorci Sanitari de Terrassa (ES)
- Complejo Hospitalario de Salamanca (ES)
- Marqués de Valdecilla University Hospital (ES)
- Hospital Infantil Universitario Niño Jesús (ES)
- Hospital Provincial de Rosario (AR)
- Vall d'Hebron Hospital Universitari (ES)
- Parc Sanitari Sant Joan de Déu (ES)
- Hospital Universitario de La Princesa (ES)
- Hospital de Mataró (ES)
- Hospital Nacional de Niños (CR)
- Institute of Research and Innovation Parc Tauli (ES)
- Hospital de Cruces (ES)
- Donostiako Unibertsitate Ospitalea (ES)
- Hospital del Niño (PA)
- Universidad de Navarra (ES)
Publication Details
- Journal
- The Pediatric Infectious Disease Journal
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1097/inf.0000000000005058
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00