Cerebral microbleeds are associated with deficits in cognitive processing speed and executive functions in middle-aged adults with type 1 diabetes
CMBs were related to a subtle, yet systematic impairment in cognition, whereas mild WMHs were not. The results provide insight into the development of early cSVD-related cognitive changes already in midlife and suggest an increased risk of cognitive decline in T1D.
Authors
- Aleksi Tarkkonen (ORCID: https://orcid.org/0000-0001-5815-6874)
- Turgut Tatlisumak
- Hanna Jokinen
- Linda Kuusela (ORCID: https://orcid.org/0000-0002-0849-8654)
- Teemu Paajanen (ORCID: https://orcid.org/0000-0003-3499-4800)
- Daniel Gordin
- Jukka Putaala
- Jussi Virkkala
- Juha Martola
- Lena M. Thorn
- Per-Henrik Groop
- Iiris Kyläheiko
Institutions
- University of Helsinki (FI)
- Helsinki University Hospital (FI)
- Sahlgrenska University Hospital (SE)
- Finnish Institute of Occupational Health (FI)
- Hospital District of Helsinki and Uusimaa (FI)
- University of Gothenburg (SE)
Publication Details
- Journal
- Diabetes Research and Clinical Practice
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1016/j.diabres.2025.113080
- Primary Topic
- Intracerebral and Subarachnoid Hemorrhage Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Eli Lilly and Company
- AstraZeneca
- Sanofi
- Helsingin Yliopisto
- Wilhelm och Else Stockmanns Stiftelse
- Folkhälsanin Tutkimussäätiö
- Minerva Foundation
- Novo Nordisk
- Samfundet Folkhälsan
- Astellas Pharma
- Sigrid Juséliuksen Säätiö
- Kymenlaakson Rahasto