Platelet-to-C-reactive protein ratio stratifies surgical risk and mortality in necrotizing enterocolitis neonates with portal venous gas

This study suggests that the PCR is a promising predictor of surgical intervention and mortality risk in NEC-PVG patients, demonstrating superior predictive performance compared to individual parameters. Based on these findings, we propose the incorporation of PCR testing into standard clinical monitoring protocols, using 4.84 × 10<sup>9</sup>/mg as a potential cutoff value to inform therapeutic decision-making. This approach may improve the clinical management and outcomes in this high-risk population.

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Publication Details

Journal
Frontiers in Pediatrics
Published
2026-01-02
DOI
https://doi.org/10.3389/fped.2025.1686076
Primary Topic
Infant Nutrition and Health
Type
article
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article

Platelet-to-C-reactive protein ratio stratifies surgical risk and mortality in necrotizing enterocolitis neonates with portal venous gas

Wei Hu, Wei Liu, Zhenhua Guo, Zhengli Wang et al.
Frontiers in Pediatrics
Infant Nutrition and Health
article

Platelet-to-C-reactive protein ratio stratifies surgical risk and mortality in necrotizing enterocolitis neonates with portal venous gas

Wei Hu, Wei Liu, Zhenhua Guo, Zhengli Wang, Xinyin Zhang, Jian Cao, Qi Tan
article en

Abstract

This study suggests that the PCR is a promising predictor of surgical intervention and mortality risk in NEC-PVG patients, demonstrating superior predictive performance compared to individual parameters. Based on these findings, we propose the incorporation of PCR testing into standard clinical monitoring protocols, using 4.84 × 10<sup>9</sup>/mg as a potential cutoff value to inform therapeutic decision-making. This approach may improve the clinical management and outcomes in this high-risk population.

Frontiers in PediatricsVol. 13
Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Good health and well-being
Openalex Percentile: Top 99%
Infant Nutrition and Health
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