Platelet-to-C-reactive protein ratio stratifies surgical risk and mortality in necrotizing enterocolitis neonates with portal venous gas
This study suggests that the PCR is a promising predictor of surgical intervention and mortality risk in NEC-PVG patients, demonstrating superior predictive performance compared to individual parameters. Based on these findings, we propose the incorporation of PCR testing into standard clinical monitoring protocols, using 4.84 × 10<sup>9</sup>/mg as a potential cutoff value to inform therapeutic decision-making. This approach may improve the clinical management and outcomes in this high-risk population.
Authors
- Wei Hu (ORCID: https://orcid.org/0000-0003-4604-8539)
- Wei Liu (ORCID: https://orcid.org/0000-0001-8211-034X)
- Zhenhua Guo (ORCID: https://orcid.org/0000-0002-9779-1587)
- Zhengli Wang
- Xinyin Zhang
- Jian Cao
- Qi Tan
Institutions
- Children's Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Frontiers in Pediatrics
- Published
- 2026-01-02
- DOI
- https://doi.org/10.3389/fped.2025.1686076
- Primary Topic
- Infant Nutrition and Health
- Type
- article
- Field-Weighted Citation Impact
- 0.00