Hemodynamic and symptomatic response in hypertrophic obstructive cardiomyopathy patients on myosin inhibitor therapy

Clinical and hemodynamic response to mavacamten was high in this real-world cohort and comparable to pivotal trial results. Incomplete response might be related to more severe baseline disease, which needs further study.

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Publication Details

Journal
Frontiers in Cardiovascular Medicine
Published
2026-01-02
DOI
https://doi.org/10.3389/fcvm.2025.1639855
Primary Topic
Cardiomyopathy and Myosin Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Hemodynamic and symptomatic response in hypertrophic obstructive cardiomyopathy patients on myosin inhibitor therapy

Roman Pfister, Athanasios Feidakis, Richard J. Nies, Monique Brüwer et al.
Frontiers in Cardiovascular Medicine
Cardiomyopathy and Myosin Studies
article

Hemodynamic and symptomatic response in hypertrophic obstructive cardiomyopathy patients on myosin inhibitor therapy

Roman Pfister, Athanasios Feidakis, Richard J. Nies, Monique Brüwer, L Pennig, Kenan Kaya, SE Baldus, Henrik ten Freyhaus, Katharina Seuthe
article en

Abstract

Clinical and hemodynamic response to mavacamten was high in this real-world cohort and comparable to pivotal trial results. Incomplete response might be related to more severe baseline disease, which needs further study.

Frontiers in Cardiovascular MedicineVol. 12
University of Cologne (DE), University Hospital Cologne (DE)
Openalex Percentile: Top 99%
Cardiomyopathy and Myosin Studies
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Hemodynamic and symptomatic response in hypertrophic obstructive cardiomyopathy patients on myosin inhibitor therapy — Roman Pfister, Athanasios Feidakis, et al. · Frontiers in Cardiovascular Medicine (2026) | TGRS Research Map | TGRS