BML-111 mitigates phosgene-induced acute lung injury in rats by activating ACE2
The findings suggest that BML-111 can alleviate phosgene-induced ALI in rats by activating ACE2, thereby inhibiting inflammatory responses and oxidative stress. BML-111 shows promise as a preventive candidate for treating phosgene-induced ALI.
Authors
- Wenli Li (ORCID: https://orcid.org/0000-0001-7509-1398)
- Zi Long (ORCID: https://orcid.org/0000-0003-3360-8963)
- Yongmei Tu (ORCID: https://orcid.org/0000-0002-2829-8916)
- Jia Hu (ORCID: https://orcid.org/0000-0001-5779-257X)
- Changyan Wang
- Zhenpeng Fan
- Xiaojie Guo
- Weihua Yu
- Deqin Kong
- Minjie Shi
- Jiangzheng Liu
Institutions
- United States Air Force (US)
- Huazhong University of Science and Technology (CN)
- Air Force Medical University (CN)
Publication Details
- Journal
- Inhalation Toxicology
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1080/08958378.2025.2607486
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00