Optimal protocol for intraoperative irrigation to prevent periprosthetic joint infection
Irrigation with 0.13% diluted povidone-iodine every 30 minutes provides the optimal balance between antimicrobial efficacy against MSSA and minimal cytotoxicity, making it the most effective strategy for preventing PJI during surgery. This study highlights the critical role of timing and frequency in povidone-iodine irrigation for reducing PJI risk.
Authors
- Tomoyuki Kataoka
- Yoshitomo Kajino (ORCID: https://orcid.org/0000-0003-1230-0011)
- Yu Yanagi
- Satoru Demura
- Musashi Ima
- Masaharu Tokoro
- Tamon Kabata
- Daisuke Inoue
Institutions
- Kanazawa University (JP)
- Shiga Medical Center (JP)
Publication Details
- Journal
- Bone and Joint Research
- Published
- 2026-01-02
- DOI
- https://doi.org/10.1302/2046-3758.151.bjr-2025-0122.r1
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00