Comparative safety and short-term outcomes of intraoperative radiotherapy versus neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a retrospective study
Single-fraction low-kV IORT provides short-term survival equivalent to standard nCRT with acceptable perioperative safety. It is a viable option for LARC patients unable or unwilling to undergo prolonged nCRT, although vigilance for early gastrointestinal and urinary complications is warranted.
Authors
- Qiangbang Yang
- Yingze Li (ORCID: https://orcid.org/0009-0005-9035-7218)
- Minghui Ma (ORCID: https://orcid.org/0000-0001-8679-2560)
- Zhijie Gong (ORCID: https://orcid.org/0009-0004-9767-9423)
- Y J He
- Yanjie Deng
- WeiWei Wang
- Jian Pan
- Jun Zhou
Institutions
- Guangdong Medical College (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Surgery
- Published
- 2026-01-02
- DOI
- https://doi.org/10.3389/fsurg.2025.1713146
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00