CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma

CD48 represents a novel immune checkpoint on TAMs critical for HCC progression and immunotherapy resistance. Targeting CD48 may overcome immunosuppression and increase therapeutic efficacy in HCC.

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Publication Details

Journal
Gut
Published
2026-01-02
DOI
https://doi.org/10.1136/gutjnl-2025-336744
Citations
1
Primary Topic
Immune cells in cancer
Type
article
Field-Weighted Citation Impact
24.43
Controls
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article

CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma

S. Wang, Zhaozhao Li, Weina Li, Yueyuan Zhou et al.
1 citations
Gut
Immune cells in cancer
24.43
article

CD48 is a novel immune checkpoint on tumour‐associated macrophages in hepatocellular carcinoma

S. Wang, Zhaozhao Li, Weina Li, Yueyuan Zhou, Lei He, G. Li, Yueyuan Qiu, Fei Xie, Jieyu Zhang, Man Li, Haichen Du, Yang Xiao, Zhaowei Wang, Yuan Gao, Yingqi Zhang, Xiaoying Lei, Wangqian Zhang, Gege Shi, Haiyan Cao, Duo Yu, Kuo Zhang
article en
1 citations

Abstract

CD48 represents a novel immune checkpoint on TAMs critical for HCC progression and immunotherapy resistance. Targeting CD48 may overcome immunosuppression and increase therapeutic efficacy in HCC.

Gut
Xijing Hospital (CN), Air Force Medical University (CN)
Good health and well-being
Openalex Percentile: Top 3%
Immune cells in cancer
24.43
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