Top 10 Questions and Answers From the National Clinician Consultation Center: What is Coming Up for Clinicians Across the United States.

The National Clinician Consultation Center (NCCC) has operated for the past 30 years as a federally supported educational resource for US clinicians, addressing a wide range of questions regarding HIV and viral hepatitis care. Changes in practice spurred on by scientific breakthroughs and new research have led to new questions and challenges for HIV practitioners. These include optimal clinical and laboratory monitoring for people receiving postexposure prophylaxis, preexposure prophylaxis, or long-acting injectable antiretroviral therapy; evolving approaches to maternal and infant antiretroviral therapy for prevention of perinatal HIV transmission; and management of comorbidities such as hepatitis C and substance use disorders. Prevalent questions received by NCCC consultants over the last 5 years are described, high-lighting key areas of HIV medicine that clinicians and clinical educators commonly face in practice, as well as opportunities for future research to address areas of ongoing clinical uncertainty.