Assessment of Dosimetric Accuracy and Plan Quality in Prostate SBRT Using RapidArc with Analysis of Varian MLC Parameters

Introduction: Prostate cancer is a highly prevalent malignancy worldwide. Advances in radiotherapy, particularly SBRT, have enabled ultra-hypofractionated treatments that improve tumor control while reducing treatment time. This study evaluates the dosimetric accuracy and plan quality of prostate SBRT delivered using RapidArc technology on a Varian Millennium Multi Leaf Collimator (MLC) system.Material and Methods: Twenty-four patients with localized prostate adenocarcinoma received SBRT with a prescribed dose of 36.25 Gy in five fractions. Treatment planning was performed using Eclipse v15.6 with the Acuros XB algorithm, employing three 6 MV Flattening Filter Free (FFF) arcs. Planning Target Volume (PTV) coverage, Organs At Risk (OAR) doses, Paddick Conformity Index (PCI), Gradient Index (GI), and Monitor Units (MU) were analyzed. MLC performance was assessed using trajectory log files to evaluate leaf speed and positional accuracy. Pre-treatment Quality Assurance (QA) was conducted using Electronic Portal Imaging Device (EPID)-based gamma analysis.Results: The mean PTV D95 was 35.80 ± 0.46 Gy, with Dmax and Dmean of 39.80 ± 1.05 Gy and 37.10 ± 0.40 Gy, respectively. V95% averaged 99.13 ± 1.14%, confirming adequate coverage. The bladder and rectum Dmax slightly exceeded constraints, while all other OAR objectives were met. Gamma pass rates exceeded 99.6% for the 2%/2mm criterion. MLC leaf speed remained below 2.5 cm/s, ensuring delivery accuracy.Conclusion: RapidArc-based prostate SBRT demonstrated high conformity, efficient delivery, and acceptable OAR sparing. Intra-fraction CBCT improved setup accuracy, and MLC log-file analysis confirmed mechanical precision, supporting the feasibility of this approach for localized prostate cancer.

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Journal
SHILAP Revista de lepidopterología
Published
2025-09-01
DOI
https://doi.org/10.22038/ijmp.2025.88593.2564
Primary Topic
Advanced Radiotherapy Techniques
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article
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article

Assessment of Dosimetric Accuracy and Plan Quality in Prostate SBRT Using RapidArc with Analysis of Varian MLC Parameters

Subhankar Show, Aaditya Prakash, Ajithkumar M
SHILAP Revista de lepidopterología
Advanced Radiotherapy Techniques
article

Assessment of Dosimetric Accuracy and Plan Quality in Prostate SBRT Using RapidArc with Analysis of Varian MLC Parameters

Subhankar Show, Aaditya Prakash, Ajithkumar M
article en

Abstract

Introduction: Prostate cancer is a highly prevalent malignancy worldwide. Advances in radiotherapy, particularly SBRT, have enabled ultra-hypofractionated treatments that improve tumor control while reducing treatment time. This study evaluates the dosimetric accuracy and plan quality of prostate SBRT delivered using RapidArc technology on a Varian Millennium Multi Leaf Collimator (MLC) system.Material and Methods: Twenty-four patients with localized prostate adenocarcinoma received SBRT with a prescribed dose of 36.25 Gy in five fractions. Treatment planning was performed using Eclipse v15.6 with the Acuros XB algorithm, employing three 6 MV Flattening Filter Free (FFF) arcs. Planning Target Volume (PTV) coverage, Organs At Risk (OAR) doses, Paddick Conformity Index (PCI), Gradient Index (GI), and Monitor Units (MU) were analyzed. MLC performance was assessed using trajectory log files to evaluate leaf speed and positional accuracy. Pre-treatment Quality Assurance (QA) was conducted using Electronic Portal Imaging Device (EPID)-based gamma analysis.Results: The mean PTV D95 was 35.80 ± 0.46 Gy, with Dmax and Dmean of 39.80 ± 1.05 Gy and 37.10 ± 0.40 Gy, respectively. V95% averaged 99.13 ± 1.14%, confirming adequate coverage. The bladder and rectum Dmax slightly exceeded constraints, while all other OAR objectives were met. Gamma pass rates exceeded 99.6% for the 2%/2mm criterion. MLC leaf speed remained below 2.5 cm/s, ensuring delivery accuracy.Conclusion: RapidArc-based prostate SBRT demonstrated high conformity, efficient delivery, and acceptable OAR sparing. Intra-fraction CBCT improved setup accuracy, and MLC log-file analysis confirmed mechanical precision, supporting the feasibility of this approach for localized prostate cancer.

SHILAP Revista de lepidopterología
Tata Main Hospital (IN)
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Openalex Percentile: Top 25%
Advanced Radiotherapy Techniques
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