Sex-Specific Association of Telomere Length with Individualized Expected Years of Life Lost among 203,731 Males and 241,668 Females.

The influence of LTL on life expectancy varies significantly by sex, with protective associations seen in males and postmenopausal females. This suggests hormonal involvement in telomere dynamics. The results support integrating sex-specific perspectives into aging and telomere research and clinical practice.

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Publication Details

Journal
PubMed
Published
2025-12-20
DOI
https://doi.org/10.3967/bes2025.053
Primary Topic
Telomeres, Telomerase, and Senescence
Type
article
Field-Weighted Citation Impact
0.00
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article

Sex-Specific Association of Telomere Length with Individualized Expected Years of Life Lost among 203,731 Males and 241,668 Females.

Hong Gang Yi, J. V. lu Dai, Fei Xu, Xiao Wang et al.
PubMed
Telomeres, Telomerase, and Senescence
article

Sex-Specific Association of Telomere Length with Individualized Expected Years of Life Lost among 203,731 Males and 241,668 Females.

Hong Gang Yi, J. V. lu Dai, Fei Xu, Xiao Wang, Zha Zheng He, Yumnah Babar, Shuang Liang, Fan Yang, Chen Jie Li, Yi Fan Wang
article en

Abstract

The influence of LTL on life expectancy varies significantly by sex, with protective associations seen in males and postmenopausal females. This suggests hormonal involvement in telomere dynamics. The results support integrating sex-specific perspectives into aging and telomere research and clinical practice.

PubMedVol. 38(12)
Nanjing Medical University (CN)
Gender equality
Openalex Percentile: Top 31%
Telomeres, Telomerase, and Senescence
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Sex-Specific Association of Telomere Length with Individualized Expected Years of Life Lost among 203,731 Males and 241,668 Females. — Hong Gang Yi, J. V. lu Dai, et al. · PubMed (2025) | TGRS Research Map | TGRS