Foundations for progress: insights from the PrEP Impact Trial supporting change to PrEP delivery and implementation in England
This analysis supports ongoing enhancements to PrEP delivery across England. Findings highlight the success of varied service models, including those not traditionally focused on MSM populations. High HIV seroconversions among individuals without clear markers of risk for HIV acquisition support the need for broader, less restrictive PrEP access, aligned with recent updates to national guidance. To evaluate the long-term impact of PrEP on HIV and sexually transmitted infection (STI) incidence, consistent, high-quality data reporting to national surveillance remains essential.
Authors
- Andrea Cartier
- James Bell (ORCID: https://orcid.org/0000-0002-2265-1205)
- Holly Mitchell (ORCID: https://orcid.org/0000-0002-6103-9975)
- Chiara Chiavenna (ORCID: https://orcid.org/0000-0003-0761-5633)
- Sajjida Jaffer
- Chris Ward (ORCID: https://orcid.org/0000-0002-2395-8452)
- John P. McSorley (ORCID: https://orcid.org/0000-0001-7197-5591)
- Dana Ogaz (ORCID: https://orcid.org/0000-0002-1900-8892)
- Rainer Golombek (ORCID: https://orcid.org/0000-0002-7539-7191)
- Victor Diamente
- John Saunders (ORCID: https://orcid.org/0000-0003-3020-9916)
- Hamish Mohammed
- AK Sullivan
- Ross Harris
- O Noel Gill
- Andre Charlett
Institutions
- Chelsea and Westminster Hospital NHS Foundation Trust (GB)
- London North West Healthcare NHS Trust (GB)
- Manchester University NHS Foundation Trust (GB)
- UK Health Security Agency (GB)
Publication Details
- Journal
- Sexually Transmitted Infections
- Published
- 2025-12-30
- DOI
- https://doi.org/10.1136/sextrans-2025-056566
- Primary Topic
- HIV/AIDS Research and Interventions
- Type
- article
- Field-Weighted Citation Impact
- 0.00