Assessment of HIF-1α and c-MYC in Breast Carcinoma and Their Association With Clinicopathological Parameters: A Cross-Sectional Study

An increase in HIF-1α expression correlated with aggressive behaviour of cancer and a higher likelihood of metastatic tumours. HIF-1α inhibitors can be considered as a newer therapeutic target.

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Publication Details

Journal
Cureus
Published
2025-12-31
DOI
https://doi.org/10.7759/cureus.100539
Primary Topic
Cancer, Hypoxia, and Metabolism
Type
article
Field-Weighted Citation Impact
0.00
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article

Assessment of HIF-1α and c-MYC in Breast Carcinoma and Their Association With Clinicopathological Parameters: A Cross-Sectional Study

Urmila Senapati, Madhusmita Mohanty, Nihar Ranjan Mohanty, Anibesh Mohapatra et al.
Cureus
Cancer, Hypoxia, and Metabolism
article

Assessment of HIF-1α and c-MYC in Breast Carcinoma and Their Association With Clinicopathological Parameters: A Cross-Sectional Study

Urmila Senapati, Madhusmita Mohanty, Nihar Ranjan Mohanty, Anibesh Mohapatra, Sabyasachi Parida
article en

Abstract

An increase in HIF-1α expression correlated with aggressive behaviour of cancer and a higher likelihood of metastatic tumours. HIF-1α inhibitors can be considered as a newer therapeutic target.

CureusVol. 17(12)
All India Institute of Medical Sciences Bhubaneswar (IN), Sri Aurobindo Institute of Medical Sciences (IN)
Good health and well-being
Openalex Percentile: Top 32%
Cancer, Hypoxia, and Metabolism
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