Association of Insulin Resistance, Sarcopenia, and Risk of Cardiovascular Disease: Findings From the China Health and Retirement Longitudinal Study

We found that IR and sarcopenia, especially early-stage sarcopenia, synergistically increase the incidence of CVD in older adults. These findings advocate for dual-targeted CVD interventions (muscle preservation and IR mitigation) in aging societies, particularly during the transitional phase of possible sarcopenia.

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Publication Details

Journal
JMIR Aging
Published
2025-12-31
DOI
https://doi.org/10.2196/80115
Primary Topic
Nutrition and Health in Aging
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of Insulin Resistance, Sarcopenia, and Risk of Cardiovascular Disease: Findings From the China Health and Retirement Longitudinal Study

Shihao Ni, Huilin Liu, WenJie Long, Sijing Li et al.
JMIR Aging
Nutrition and Health in Aging
article

Association of Insulin Resistance, Sarcopenia, and Risk of Cardiovascular Disease: Findings From the China Health and Retirement Longitudinal Study

Shihao Ni, Huilin Liu, WenJie Long, Sijing Li, Huili Liao, Zhongqi Yang, Lu Lu, Ximin Zhang
article en

Abstract

We found that IR and sarcopenia, especially early-stage sarcopenia, synergistically increase the incidence of CVD in older adults. These findings advocate for dual-targeted CVD interventions (muscle preservation and IR mitigation) in aging societies, particularly during the transitional phase of possible sarcopenia.

JMIR AgingVol. 8
Guangzhou University of Chinese Medicine (CN), First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 31%
Nutrition and Health in Aging
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Association of Insulin Resistance, Sarcopenia, and Risk of Cardiovascular Disease: Findings From the China Health and Retirement Longitudinal Study — Shihao Ni, Huilin Liu, et al. · JMIR Aging (2025) | TGRS Research Map | TGRS