Choroidal Osteoma Complicated by Choroidal Neovascularization: A Case Report

A 13-year-old girl with no prior systemic or ocular comorbidities presented to the eye clinic at Shifa International Hospital, Islamabad, Pakistan, with complaints of blurred vision in her left eye. Fundus examination revealed a well-defined, yellow-orange lesion at the posterior pole. B-scan ultrasonography demonstrated an echo-dense lesion, most prominent at low gain, while swept source optical coherence tomography (SS-OCT) showed a hyperreflective choroidal mass with associated subretinal fluid (SRF). Based on these findings, a diagnosis of choroidal osteoma complicated by choroidal neovascularization (CNV) was established. This case report describes the management of a pediatric case of CNV related to choroidal osteoma with a series of intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections over nine months, resulting in significant regression of CNV and a reduction in SRF. She continues to be monitored with multimodal imaging and intermittent therapy, demonstrating favorable anatomical and functional outcomes.

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Publication Details

Journal
Cureus
Published
2025-12-31
DOI
https://doi.org/10.7759/cureus.100540
Primary Topic
Ocular Oncology and Treatments
Type
article
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OCT
article

Choroidal Osteoma Complicated by Choroidal Neovascularization: A Case Report

Aisha Ahmed Khan, Muhammad Amer Awan, Zaid Azhar
Cureus
Ocular Oncology and Treatments
article

Choroidal Osteoma Complicated by Choroidal Neovascularization: A Case Report

Aisha Ahmed Khan, Muhammad Amer Awan, Zaid Azhar
article en

Abstract

A 13-year-old girl with no prior systemic or ocular comorbidities presented to the eye clinic at Shifa International Hospital, Islamabad, Pakistan, with complaints of blurred vision in her left eye. Fundus examination revealed a well-defined, yellow-orange lesion at the posterior pole. B-scan ultrasonography demonstrated an echo-dense lesion, most prominent at low gain, while swept source optical coherence tomography (SS-OCT) showed a hyperreflective choroidal mass with associated subretinal fluid (SRF). Based on these findings, a diagnosis of choroidal osteoma complicated by choroidal neovascularization (CNV) was established. This case report describes the management of a pediatric case of CNV related to choroidal osteoma with a series of intravitreal anti-vascular endothelial growth factor (anti-VEGF) injections over nine months, resulting in significant regression of CNV and a reduction in SRF. She continues to be monitored with multimodal imaging and intermittent therapy, demonstrating favorable anatomical and functional outcomes.

CureusVol. 17(12)
Shifa Tameer-e-Millat University (PK), Shifa International Hospital (PK)
Good health and well-being, Gender equality
Openalex Percentile: Top 27%
Ocular Oncology and Treatments
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Choroidal Osteoma Complicated by Choroidal Neovascularization: A Case Report — Aisha Ahmed Khan, Muhammad Amer Awan, et al. · Cureus (2025) | TGRS Research Map | TGRS