Association Between Circulating Cytokines and Psychosomatic Syndromes in Patients with Mood Disorders.

findings suggest that the link between inflammation and mood disorders is more closely related to psychosomatic syndromes than to mood symptoms alone. Elevated IL-6 levels may reflect somatization processes within depression rather than being directly pro-depressive. Psychosomatic syndromes may thus represent a key clinical and therapeutic target in mood disorders with elevated inflammation.

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Publication Details

Journal
PubMed
Published
2025-12-01
DOI
https://doi.org/10.36131/cnfioritieditore20250605
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Association Between Circulating Cytokines and Psychosomatic Syndromes in Patients with Mood Disorders.

Livia Ficarella, Benedetta Vai, Rossana Laurello, Michele Carapellese et al.
PubMed
Tryptophan and brain disorders
article

Association Between Circulating Cytokines and Psychosomatic Syndromes in Patients with Mood Disorders.

Livia Ficarella, Benedetta Vai, Rossana Laurello, Michele Carapellese, Francesco Benedetti, Ivana Leccisotti, Mario Altamura, Antonello Bellomo
article en

Abstract

findings suggest that the link between inflammation and mood disorders is more closely related to psychosomatic syndromes than to mood symptoms alone. Elevated IL-6 levels may reflect somatization processes within depression rather than being directly pro-depressive. Psychosomatic syndromes may thus represent a key clinical and therapeutic target in mood disorders with elevated inflammation.

PubMedVol. 22(6)
University of Foggia (IT), Vita-Salute San Raffaele University (IT), IRCCS Ospedale San Raffaele (IT)
Good health and well-being
Openalex Percentile: Top 46%
Tryptophan and brain disorders
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