Not Your Usual Staph: Recurrent Human Infection With the Canine-Associated Staphylococcus pseudintermedius

<i>Staphylococcus pseudintermedius</i> is a coagulase-positive bacterium commonly found as part of the normal flora in healthy dogs. In clinical settings, infections caused by <i>S. pseudintermedius</i> are often misidentified as <i>Staphylococcus aureus</i> due to similarities in morphology and the relative rarity of <i>S. pseudintermedius</i> as a documented human pathogen. Close contact with dogs has been associated with human infection, but the exact frequency and mechanism of zoonotic transmission remain unclear. Accurate and timely identification of the <i>Staphylococcus</i> species is essential for appropriate treatment. We present a case of <i>S. pseudintermedius</i> infection likely transmitted from a patient's household dog. The zoonotic origin of the infection was initially unrecognized, as its clinical significance was misjudged. However, the patient experienced a complicated course with recurrent skin and soft tissue infections, highlighting the diagnostic and treatment challenges of zoonotic <i>S. pseudintermedius</i> infections.

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Journal
Cureus
Published
2025-12-31
DOI
https://doi.org/10.7759/cureus.100522
Primary Topic
Antimicrobial Resistance in Staphylococcus
Type
article
Field-Weighted Citation Impact
0.00
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article

Not Your Usual Staph: Recurrent Human Infection With the Canine-Associated Staphylococcus pseudintermedius

Elizabeth Chung, Robert M. Jellinger, Nino Marzella, Aahana Gaur et al.
Cureus
Antimicrobial Resistance in Staphylococcus
article

Not Your Usual Staph: Recurrent Human Infection With the Canine-Associated Staphylococcus pseudintermedius

Elizabeth Chung, Robert M. Jellinger, Nino Marzella, Aahana Gaur, Anna D Kamuda, Michael Woo
article en

Abstract

<i>Staphylococcus pseudintermedius</i> is a coagulase-positive bacterium commonly found as part of the normal flora in healthy dogs. In clinical settings, infections caused by <i>S. pseudintermedius</i> are often misidentified as <i>Staphylococcus aureus</i> due to similarities in morphology and the relative rarity of <i>S. pseudintermedius</i> as a documented human pathogen. Close contact with dogs has been associated with human infection, but the exact frequency and mechanism of zoonotic transmission remain unclear. Accurate and timely identification of the <i>Staphylococcus</i> species is essential for appropriate treatment. We present a case of <i>S. pseudintermedius</i> infection likely transmitted from a patient's household dog. The zoonotic origin of the infection was initially unrecognized, as its clinical significance was misjudged. However, the patient experienced a complicated course with recurrent skin and soft tissue infections, highlighting the diagnostic and treatment challenges of zoonotic <i>S. pseudintermedius</i> infections.

CureusVol. 17(12)
State University of New York (US), Long Island University (US), SUNY Downstate Health Sciences University (US), VA NY Harbor Healthcare System (US)
Openalex Percentile: Top 29%
Antimicrobial Resistance in Staphylococcus
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Not Your Usual Staph: Recurrent Human Infection With the Canine-Associated Staphylococcus pseudintermedius — Elizabeth Chung, Robert M. Jellinger, et al. · Cureus (2025) | TGRS Research Map | TGRS