Mixed Methods Systematic Review Approach to Combine Quantitative Evidence And Qualitative Evidence

Purpose: This article aims to provide detailed information on mixed methods systematic reviews (MMSRs), including formulating review questions, related processes focused on a convergent integrated approach, and integrating qualitative and quantitative review evidence, and to suggest recommendations for reviewers undertaking MMSRs. Methods: This article provides a brief introduction to the researchers on the purpose of MMSRs, the methodological framework with related examples, and practical tips for conducting MMSRs. Results: MMSRs are a relatively emerging approach to evidence synthesis methods that provide a line of argument or overall configuration derived from primary quantitative, qualitative, or mixed-methods research. By integrating quantitative and qualitative synthesized findings, a deeper understanding of the phenomenon of interest can be obtained, particularly for complex interventions in health systems or public health contexts. Conclusion: Due to the complex process of conducting MMSRs, reviewers need to adhere to methodological guidance to enhance the validity and robustness of review findings.